The toxicity of fumonisin B1on some biochemical and immunological parameters and its detoxification by red cabbage and garlic

The protective effects of red cabbage and garlic extracts against liver, kidney thyroid gland damage induced by fumonisin B1 (FB1) in male mice were studied. Sixty divided to six groups. Group one are the healthy mice, two that received a daily oral dose only FB-1 (100 µg/kg.b.w) for 1 month, three: extract (500 mg/kg.bw) plus FB1, four: extracts, five: (500mg/kg.bw) group 6:are extract. After finishing experiments, samples blood used biochemical examination. results indicated (2) treated with had significantly increased levels immunoglobulins (IgG IgM), function parameters (urea creatinine), proteins (albumin total protein (TP)), hormones (T3 T4), along decreased level TSH (p < 0.05). In LD50 experiment, we choose concentration gavage mice. Oral administration produced significantl reduction serum IgG, IgM, T3, T4, urea, creatinine, TP albumin significant increase TSH.